Inhalation Technology

Why Inhaled Therapies

Delivery of therapeutics directly to the lungs allows for more precise doses of drugs to achieve therapeutic benefit and avoid adverse events seen with orals and injectables.

For a number of cardiopulmonary conditions, treatment via inhalation is an ideal alternative to routine injections allowing for improved drug bioavailability and efficacy while providing a better patient experience.

Proprietary Inhalation Technology

Successful aerosol drug-device combinations depend on optimum device characteristics and performance. Our breath actuated inhalers are designed to improve the effectiveness of inhaled drugs, deliver better clinical outcomes and provide shorter treatment time.

The AFINA™ Experience

AFINA is designed with smart technology to optimize the precise delivery of therapeutics to the lungs in seconds.

How AFINA Works

The AFINA Inhaler uses smart technology – it is breath actuated with a visual indicator that lights up with constant green to indicate optimal breathing or flashes if the patient inhales too fast or slow – ensuring precise delivery of the drug through the lungs for local or systemic therapeutic effect. It is Bluetooth-enabled with real time data collection.

The AFINA Inhaler is powered by a vibrating mesh technology. It has a palladium-nickel coated mesh with thousands of tiny funnel-like holes. When the mesh vibrates 128,000 times per second, the liquid drug formulation gets pushed through the funnel, turning it into a fine mist of tiny droplets which are the right size to breathe in. The design of the inhaler allows the aerosol flow to be laminar, instead of turbulent, so more particles are delivered to the lungs rather than to the back of the throat, and, as a result, there is no coughing associated with inhalation of the gentle mist. The AFINA Inhaler delivers approximately 80% of the drug to the lungs which is 2-4 times higher than conventional inhalers – enabling efficient delivery of the right dose of drug in a short amount of time.

Novel formulations

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Novel formulations:

  • Compatible for use with multiple biologic formulations
  • Stable formulations for long-term viability

Drop dispenser

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Drop dispenser:

  • Easily loaded
    and cleaned
  • No need for refrigeration
  • Strong, sterile
    anti-microbial barrier

Mesh technology

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Mesh technology:

  • State-of the art vibrating mesh technology
  • 120,000 vibrations
    per second

Smart inhaler

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Smart inhaler:

  • Breath-activated for precise dosing
  • > 80% drug deposition deep in the lungs
  • Silent and discreet
  • Pocket size